Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269542 | 0.87 | MAPT (0.66) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL11115997 | 0.87 | KMT2A (0.66) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL10830747 | 0.86 | ALOX5 (0.72) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL7015882 | 0.84 | ALOX5 (0.65) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL10597312 | 0.83 | NPC1 (0.57) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL28433164 | 0.83 | LMNA (0.53) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL11177144 | 0.82 | MAPT (0.58) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| Benzene SCHEMBL7330438 | 0.82 | ALOX5 (0.61) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL4678684 | 0.81 | KMT2A (0.62) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL9622398 | 0.80 | SMN1; SMN2 (0.71) | ALDH1A1KMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367233-A | ALPHA-PHENYL-2-/AZA/BENZOTHIAZOYLTHIOGLYCOLIC ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-01-04 | — | — | US | claimed |
| EP-0021773-B1 | THIAZOLO (2,3-B) BENZO (AND AZABENZO) THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-01 | — | — | EP | disclosed |
| EP-0006347-B1 | COMPOSITIONS AND METHOD FOR REGULATING SOYBEAN PLANT GROWTH UTILIZING SUBSTITUTED BENZAZOLYLTHIOALKANOIC ACIDS | MONSANTO COMPANY (US) | 1984-01-25 | — | — | EP | disclosed |
| US-4367233-A | ALPHA-PHENYL-2-/AZA/BENZOTHIAZOYLTHIOGLYCOLIC ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| US-4275065-A | USEFUL FOR SKIN GRAFTS AND ORGAN TRANSPLANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-23 | — | — | US | disclosed |
| EP-0021773-A1 | Thiazolo (2,3-b) benzo (and azabenzo) thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-01-07 | — | — | EP | disclosed |