Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624480 | 0.84 | ALDH1A1 (0.74) | ALOX5MAPTHSD17B10POLBL3MBTL1 | |
| SCHEMBL11099223 | 0.82 | ALDH1A1 (0.65) | ALOX5MAPTHSD17B10POLBL3MBTL1 | |
| SCHEMBL11115997 | 0.79 | KMT2A (0.66) | ALOX5MAPTHSD17B10POLBL3MBTL1 | |
| SCHEMBL1269542 | 0.79 | MAPT (0.66) | ALOX5MAPTHSD17B10POLBL3MBTL1 | |
| SCHEMBL7334028 | 0.78 | PPARA (0.71) | ALOX5PPARA | |
| SCHEMBL29213218 | 0.77 | ALDH1A1 (0.64) | ALOX5MAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL9439564 | 0.77 | ALOX5 (0.64) | ALOX5MAPTHSD17B10KMT2AALDH1A1 | |
| SCHEMBL11402240 | 0.77 | PPARA (0.57) | ALOX5MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL11177144 | 0.77 | MAPT (0.58) | ALOX5MAPTHSD17B10POLBL3MBTL1 | |
| SCHEMBL10359257 | 0.76 | PTPN1 (0.56) | ALOX5MAPTPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067685-B1 | ALPHA-PHENYL-2-(AZA)BENZOTHIAZOLYLTHIOGLYCOLIC ACIDS AND DERIVATIVES THEREOF | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4567267-A | α-Phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
| US-4367233-A | ALPHA-PHENYL-2-/AZA/BENZOTHIAZOYLTHIOGLYCOLIC ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| EP-0067685-A1 | Alpha-phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-12-22 | — | — | EP | disclosed |