Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Protiofate SCHEMBL871311 | 0.82 | MAPT (0.50) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| SCHEMBL1141274 | 0.82 | GAA (0.56) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| SCHEMBL1726035 | 0.80 | GAA (0.55) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| Lithium SCHEMBL7065338 | 0.80 | GAA (0.55) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| Potassium SCHEMBL7063916 | 0.80 | GAA (0.55) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| SCHEMBL11099805 | 0.76 | HSD17B10 (0.44) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| SCHEMBL14650156 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| SCHEMBL6206616 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| SCHEMBL2935502 | 0.74 | ESR1 (0.49) | ALDH1A1TSHRRAB9ASMN1; SMN2POLB | |
| SCHEMBL11399022 | 0.74 | MC4R (0.53) | ALDH1A1TSHRGAAHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032748-B1 | THIOPHENE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |
| US-4421761-A | FUNGICIDES | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0032748-A1 | Thiophene derivatives | UBE INDUSTRIES, LTD. (JP) | 1981-07-29 | — | — | EP | disclosed |