Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424271 | 0.83 | LTA4H (0.44) | ALDH1A1IDO1 | |
| SCHEMBL949991 | 0.79 | CALM1 (0.49) | CALM1POLBALDH1A1ALOX5F2RL1 | |
| SCHEMBL244070 | 0.75 | CALM1 (0.79) | CALM1ALOX5TAAR1IGF1RALOX15 | |
| SCHEMBL10564786 | 0.72 | CALM1 (0.50) | CALM1POLBALDH1A1ALOX5TAAR1 | |
| SCHEMBL5046188 | 0.71 | CALM1 (0.49) | CALM1POLBALDH1A1ALOX5TAAR1 | |
| SCHEMBL4254058 | 0.71 | CALM1 (0.72) | CALM1ALOX5TAAR1IGF1RALOX15 | |
| SCHEMBL11007798 | 0.69 | CALM1 (0.69) | CALM1ALOX5TAAR1IGF1RALOX15 | |
| SCHEMBL10571532 | 0.69 | CALM1 (0.69) | CALM1ALOX5TAAR1IGF1RALOX15 | |
| SCHEMBL17400406 | 0.69 | CALM1 (0.69) | CALM1ALOX5TAAR1IGF1RALOX15 | |
| SCHEMBL9509173 | 0.69 | CALM1 (0.69) | CALM1ALOX5TAAR1IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125033-A1 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BECKMAN CORPORATION (US) | 1984-11-14 | — | — | EP | disclosed |