Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095441 | 0.88 | MCL1 (0.70) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL719607 | 0.86 | MCL1 (0.63) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL11095152 | 0.84 | PKM (0.64) | MCL1KCNH2KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11100621 | 0.83 | RAB9A (0.55) | MCL1KDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL14648196 | 0.83 | MCL1 (0.77) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL11686876 | 0.83 | MCL1 (0.77) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL4615856 | 0.83 | MCL1 (1.00) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL15619301 | 0.80 | MCL1 (0.77) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL11098041 | 0.79 | NPC1 (0.64) | KDM4EALDH1A1HPGDSMN1; SMN2RXFP1 | |
| SCHEMBL23665874 | 0.79 | MCL1 (0.70) | MCL1KCNH2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045473-B1 | A PHARMACEUTICAL COMPOSITION CONTAINING A BENZOFURAN-CARBOXAMIDE DERIVATIVE AS THE ACTIVE INGREDIENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-05-02 | — | — | EP | claimed |
| US-4353923-A | MUSCLE RELAXANTS, ANTIINFLAMMATORY, ANALGESIC | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-10-12 | — | — | US | claimed |
| EP-0045473-A1 | A pharmaceutical composition containing a benzofuran-carboxamide derivative as the active ingredient | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-02-10 | — | — | EP | claimed |