Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 12/20 | 0.52 |
| ▸ | IKBKE | Q14164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11125441 | 0.91 | TBK1 (0.46) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11394398 | 0.90 | TBK1 (0.43) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11102016 | 0.89 | TBK1 (0.49) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11096162 | 0.88 | TBK1 (0.54) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11098817 | 0.87 | RAB9A (0.43) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11102394 | 0.86 | TBK1 (0.48) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11389432 | 0.85 | MEN1 (0.51) | KDM4ENPC1RAB9APKMGPR35 | |
| SCHEMBL11099409 | 0.84 | KMT2A (0.48) | TBK1KDM4ENPC1RAB9ATTR | |
| SCHEMBL2901850 | 0.81 | TBK1 (0.72) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11102044 | 0.81 | TBK1 (0.56) | TBK1IKBKEKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026675-B1 | 1-AZAXANTHONE-3-CARBOXYLIC ACIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1984-03-14 | — | — | EP | claimed |
| US-4302463-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-24 | — | — | US | claimed |
| EP-0026675-B1 | 1-AZAXANTHONE-3-CARBOXYLIC ACIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4302463-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-24 | — | — | US | disclosed |