Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107427 | 0.86 | RAB9A (0.55) | KMT2AMEN1NPC1RAB9AMAOB | |
| SCHEMBL11389432 | 0.85 | MEN1 (0.51) | KMT2AMEN1NPC1RAB9ATTR | |
| SCHEMBL11099321 | 0.84 | TBK1 (0.52) | KMT2AMEN1NPC1RAB9ATBK1 | |
| SCHEMBL11544400 | 0.80 | MEN1 (0.68) | KMT2AMEN1NPC1RAB9ATBK1 | |
| SCHEMBL11356167 | 0.79 | TBK1 (0.52) | KMT2AMEN1NPC1RAB9ATBK1 | |
| SCHEMBL2901859 | 0.78 | TBK1 (0.58) | KMT2AMEN1NPC1RAB9ATBK1 | |
| SCHEMBL11550388 | 0.78 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9ATBK1 | |
| SCHEMBL11364238 | 0.77 | RAB9A (0.57) | KMT2AMEN1NPC1RAB9AMAOA | |
| SCHEMBL11099411 | 0.76 | KMT2A (0.50) | KMT2AMEN1NPC1RAB9ATBK1 | |
| SCHEMBL11358780 | 0.75 | RAB9A (0.60) | KMT2AMEN1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302463-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-24 | — | — | US | claimed |
| EP-0026675-B1 | 1-AZAXANTHONE-3-CARBOXYLIC ACIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4302463-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-24 | — | — | US | disclosed |