Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206268 | 0.81 | DDB1 (0.47) | SLC6A4GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8018754 | 0.77 | ALDH1A1 (0.45) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15282087 | 0.77 | SRD5A1 (0.43) | SRD5A1SLC6A2SLC6A4SLC6A3POLB | |
| SCHEMBL11093631 | 0.75 | ALDH1A1 (0.42) | GAAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11760775 | 0.72 | HTR2A (0.50) | SRD5A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10177662 | 0.71 | HTR3A (0.42) | SRD5A1USP30SLC6A2SLC6A3MAPT | |
| SCHEMBL512106 | 0.71 | SRD5A1 (0.41) | SRD5A1SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL8029062 | 0.70 | DDB1 (0.46) | MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL1616775 | 0.69 | KDM4E (0.42) | SRD5A1MAPTTP53POLBKDM4E | |
| SCHEMBL15874655 | 0.69 | KDM4E (0.42) | SRD5A1MAPTTP53POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |