Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625754 | 0.82 | GAA (0.52) | ALDH1A1KMT2ATSHRMEN1MAPK1 | |
| SCHEMBL9311658 | 0.80 | CYP1A2 (0.42) | ALDH1A1KMT2ATSHRMEN1MAPK1 | |
| SCHEMBL3283957 | 0.79 | HMGB1 (0.42) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11099358 | 0.79 | CYP2C19 (0.41) | ALDH1A1KMT2ATSHRMEN1MAPT | |
| SCHEMBL10627019 | 0.79 | GAA (0.43) | ALDH1A1KMT2ATSHRMEN1MAPK1 | |
| SCHEMBL9507159 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2ATSHRMEN1MAPK1 | |
| Bicarbonate SCHEMBL11433304 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2ATSHRMEN1MAPK1 | |
| SCHEMBL5872981 | 0.77 | HSPA5 (0.44) | ALDH1A1KMT2ATSHRMEN1MAPK1 | |
| SCHEMBL28782150 | 0.76 | ESR1 (0.41) | KMT2AGAAHMGCR | |
| SCHEMBL8527204 | 0.76 | VCAM1 (0.37) | ALDH1A1KMT2ATSHRMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1420891-A | Pharmaceutical compounds | NICOX SA (FR) | 2003-05-28 | — | — | CN | claimed |
| CN-1354740-A | Pharmaceutical compounds | NICOX SA (FR) | 2002-06-19 | — | — | CN | claimed |
| EP-1192129-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2002-04-03 | — | — | EP | claimed |
| WO-2000061549-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | claimed |
| CN-1916013-A | Pharmaceutical compounds | NICOX SA (FR) | 2007-02-21 | — | — | CN | disclosed |
| CN-1420891-A | Pharmaceutical compounds | NICOX SA (FR) | 2003-05-28 | — | — | CN | disclosed |
| CN-1354740-A | Pharmaceutical compounds | NICOX SA (FR) | 2002-06-19 | — | — | CN | disclosed |
| US-5110978-A | PROCESS FOR THE PREPARATION OF PHENOLIC THIOCARBOXYLIC ACID ESTERS | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |