Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099640 | 1.00 | RECQL (0.51) | RECQLNFE2L2MEN1KMT2AMAPT | |
| SCHEMBL746313 | 0.77 | RECQL (0.55) | RECQLNFE2L2MEN1KMT2AMAPT | |
| SCHEMBL5215991 | 0.77 | RECQL (0.55) | RECQLNFE2L2MEN1KMT2AMAPT | |
| SCHEMBL746312 | 0.77 | RECQL (0.55) | RECQLNFE2L2MEN1KMT2AMAPT | |
| SCHEMBL5954099 | 0.77 | RECQL (0.55) | RECQLNFE2L2MEN1KMT2AMAPT | |
| SCHEMBL2165184 | 0.77 | RECQL (0.55) | RECQLNFE2L2MEN1KMT2AMAPT | |
| SCHEMBL4595327 | 0.77 | NPC1 (0.62) | NFE2L2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14904519 | 0.77 | NFE2L2 (0.54) | RECQLNFE2L2MEN1KMT2AMAPT | |
| SCHEMBL28618284 | 0.74 | ALDH1A1 (0.50) | KMT2AMAPTKDM4ELMNAPKM | |
| SCHEMBL28605730 | 0.74 | CHRM5 (0.64) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013111-B1 | 3'-(SUBSTITUTED PHENYL)-SPIRO(ISOBENZOFURAN-1(3H),5'(4'H)-ISOXAZOL)-3-ONES, PROCESS FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND PLANT GROWTH REGULANTS AND THEIR APPLICATION TO THE PREPARATION OF ISOXAZOLE DERIVATIVES | MONSANTO COMPANY (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4401457-A | 3'-(Substituted phenyl)-spiro[isobenzofuran-1(3H),5'(4'H)-isoxazol]-3-ones and their use as herbicides | MONSANTO COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| US-4364768-A | FOR LEGUMES | MONSANTO COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| EP-0013111-A2 | 3'-(substituted phenyl)-spiro(isobenzofuran-1(3H),5'(4'H)-isoxazol)-3-ones, process for their preparation, their use as herbicides and plant growth regulants and their application to the preparation of isoxazole derivatives | MONSANTO COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |
| US-4209629-A | HERBICIDES, PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1980-06-24 | — | — | US | disclosed |