Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25261692 | 0.85 | ALDH1A1 (0.41) | KDM4ERECQLPKMALDH1A1HPGD | |
| SCHEMBL11392001 | 0.84 | GPR17 (0.42) | KDM4EALDH1A1GPR17HRH3LMNA | |
| SCHEMBL14988768 | 0.83 | NPSR1 (0.57) | KDM4EGPR17HRH3POLBTSHR | |
| SCHEMBL6017716 | 0.83 | GPR17 (0.41) | KDM4EALDH1A1GPR17HRH3LMNA | |
| SCHEMBL15319053 | 0.81 | NPSR1 (0.39) | KDM4ERECQLPKMALDH1A1GPR17 | |
| SCHEMBL11505002 | 0.80 | ALDH1A1 (0.37) | KDM4ERECQLPKMALDH1A1HPGD | |
| SCHEMBL9632300 | 0.80 | ALDH1A1 (0.54) | KDM4ERECQLPKMALDH1A1LMNA | |
| SCHEMBL10868522 | 0.80 | ALDH1A1 (0.46) | KDM4ERECQLPKMALDH1A1GPR17 | |
| SCHEMBL7193838 | 0.79 | ALDH1A1 (0.42) | KDM4EALDH1A1GPR17HRH3HPGD | |
| SCHEMBL26802127 | 0.79 | KDM4E (0.42) | KDM4ERECQLPKMALDH1A1GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128642-A1 | Herbicidal compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-19 | — | — | EP | disclosed |
| EP-0080301-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-06-01 | — | — | EP | disclosed |