Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GGT1 | P19440 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593297 | 0.86 | HTR4 (0.58) | KMT2AMEN1HTR4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL594135 | 0.85 | HTR4 (0.57) | KMT2AMEN1HTR4NPC1RAB9A | |
| SCHEMBL1753596 | 0.82 | RAB9A (0.55) | ALDH1A1HPGDKMT2AMEN1HTR4 | |
| SCHEMBL5482447 | 0.80 | RAB9A (0.56) | ALDH1A1HPGDKMT2AMEN1HTR4 | |
| SCHEMBL29493491 | 0.79 | DHODH (0.51) | ALDH1A1KMT2AMEN1HTR4SGMS2 | |
| SCHEMBL594263 | 0.79 | NPC1 (0.72) | ALDH1A1KMT2AMEN1HTR4NPC1 | |
| SCHEMBL1753490 | 0.78 | DRD4 (0.55) | KMT2AMEN1HTR4NPC1RAB9A | |
| SCHEMBL28397953 | 0.78 | MEN1 (0.79) | ALDH1A1KMT2AMEN1SGMS2NPC1 | |
| SCHEMBL31465178 | 0.77 | NPC1 (0.71) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL30201998 | 0.76 | HTR4 (0.49) | ALDH1A1KDM4EHPGDKMT2AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064255-B1 | BENZOPYRANYL ETHERS, PROCESS FOR THEIR PREPARATION AND MEDICINE CONTAINING THOSE COMPOUNDS AND INTERMEDIATES | Roche Diagnostics GmbH (DE) | 1984-12-12 | — | — | EP | disclosed |
| US-4428955-A | ALLERGIC DISEASES | BOEHRINGER MANNHEIM GMBH (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0064255-A1 | Benzopyranyl ethers, process for their preparation and medicine containing those compounds and intermediates | Roche Diagnostics GmbH (DE) | 1982-11-10 | — | — | EP | disclosed |