Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753596 | 0.95 | RAB9A (0.55) | RAB9AL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL593297 | 0.92 | HTR4 (0.58) | RAB9AL3MBTL1ATMKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL594135 | 0.91 | HTR4 (0.57) | RAB9AL3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL11236668 | 0.87 | RAB9A (0.71) | RAB9AL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL1753490 | 0.85 | DRD4 (0.55) | RAB9AL3MBTL1KMT2AMEN1HTR4 | |
| SCHEMBL2542357 | 0.83 | TAS1R3 (0.68) | RAB9AL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL11099692 | 0.80 | ALDH1A1 (0.49) | RAB9AALDH1A1KMT2AMEN1SGMS2 | |
| SCHEMBL5476430 | 0.78 | NPC1 (0.56) | RAB9AL3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL8219157 | 0.77 | BRPF1 (0.51) | RAB9AKMT2AHTR4NPC1GAA | |
| SCHEMBL7300279 | 0.77 | MEN1 (0.51) | KMT2AMEN1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072892-A1 | Amino-aza-adamantane derivatives and methods of use | ABBOTT LABORATORIES | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072892-A1 | Amino-aza-adamantane derivatives and methods of use | CHRNA7, CHRNA5, CHRNA1 | RAB9A 908/4885L3MBTL1 3923/4885ATM 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.