Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.59 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683339 | 0.88 | CHRNA7 (0.52) | ACHEALDH1A1TDP1CHRNA7NPSR1 | |
| SCHEMBL11777390 | 0.81 | CYP3A4 (0.38) | ACHETEAD4ALDH1A1MAPTCHRNA7 | |
| SCHEMBL11777251 | 0.79 | ALDH1A1 (0.41) | ACHETEAD4ALDH1A1TDP1MAPT | |
| SCHEMBL11500414 | 0.79 | LMNA (0.46) | ACHECHRNA7NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL3924304 | 0.79 | IDO1 (0.47) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL8208247 | 0.78 | ACHE (0.68) | ACHETEAD4ALDH1A1TDP1MAPT | |
| SCHEMBL17737832 | 0.78 | ACHE (0.68) | ACHETEAD4ALDH1A1TDP1MAPT | |
| SCHEMBL4059207 | 0.77 | ACHE (0.59) | ACHEALDH1A1TDP1MAPTPOLB | |
| SCHEMBL9771532 | 0.77 | IDO1 (0.50) | TDP1POLBCHRNA7MAPK1SMN1; SMN2 | |
| SCHEMBL11778678 | 0.77 | IDO1 (0.56) | ALDH1A1TDP1MAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113922-A2 | Process for the manufacture of cationic methine dyes | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-3956264-A | Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |