Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104537 | 0.89 | PIK3CD (0.56) | PIK3CDPIK3R1ALDH1A1HTR1BHTR1D | |
| SCHEMBL11112404 | 0.78 | PIK3CD (0.53) | PIK3CDPIK3R1HTR1BHTR1DHTR7 | |
| SCHEMBL11108346 | 0.78 | PDE5A (0.41) | PIK3CDPIK3R1ALDH1A1LDHA | |
| SCHEMBL11109514 | 0.77 | PIK3CD (0.57) | PIK3CDPIK3R1ALDH1A1HTR1BHTR1D | |
| SCHEMBL9471998 | 0.73 | PIK3CD (0.51) | PIK3CDPIK3R1ALDH1A1HTR1BHTR1D | |
| SCHEMBL24718609 | 0.73 | GALR3 (0.39) | PIK3CDPIK3R1ALDH1A1NPC1RAB9A | |
| SCHEMBL11102255 | 0.73 | PIK3CD (0.53) | PIK3CDPIK3R1HTR1BHTR1DHTR7 | |
| SCHEMBL4308925 | 0.73 | PIK3CD (0.52) | PIK3CDPIK3R1ALDH1A1HTR1BHTR1D | |
| SCHEMBL11100914 | 0.73 | L3MBTL1 (0.46) | PIK3CDPIK3R1ALDH1A1LDHA | |
| SCHEMBL11110639 | 0.73 | DRD2 (0.43) | PIK3CDPIK3R1ALDH1A1HTR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |