Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 12/20 | 0.46 |
| ▸ | DRD4 | P21917 | 12/20 | 0.46 |
| ▸ | DRD3 | P35462 | 9/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101849 | 0.84 | DRD2 (0.47) | HTR1BDRD2DRD4DRD3 | |
| SCHEMBL11290156 | 0.83 | LMNA (0.46) | PIK3CDPIK3R1DRD2DRD4DRD3 | |
| SCHEMBL11109561 | 0.82 | DRD2 (0.47) | PIK3CDPIK3R1DRD2DRD4DRD3 | |
| SCHEMBL11102255 | 0.81 | PIK3CD (0.53) | PIK3CDPIK3R1HTR1BDRD2DRD4 | |
| SCHEMBL11104537 | 0.81 | PIK3CD (0.56) | PIK3CDPIK3R1HTR1BDRD2DRD4 | |
| SCHEMBL11110238 | 0.80 | LMNA (0.45) | PIK3CDPIK3R1L3MBTL1 | |
| SCHEMBL11102550 | 0.80 | DRD2 (0.45) | PIK3CDPIK3R1HTR1BDRD2DRD4 | |
| SCHEMBL11103109 | 0.79 | PIK3CD (0.51) | PIK3CDPIK3R1HTR1BDRD2DRD4 | |
| SCHEMBL11109514 | 0.79 | PIK3CD (0.57) | PIK3CDPIK3R1HTR1BDRD2DRD4 | |
| SCHEMBL11101221 | 0.78 | PIK3CD (0.54) | PIK3CDPIK3R1HTR1BDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |