Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101235 | 1.00 | FBP1 (0.62) | FBP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL28313969 | 0.86 | FBP1 (0.56) | FBP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL17009045 | 0.84 | AKR1C3 (0.58) | FBP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL52681 | 0.84 | AKR1C3 (0.58) | FBP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL481147 | 0.84 | AKR1C3 (0.58) | FBP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8009563 | 0.83 | MAPT (0.60) | FBP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL9065473 | 0.83 | MAPT (0.60) | FBP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL11100277 | 0.81 | GLO1 (0.68) | FBP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11100274 | 0.81 | GLO1 (0.68) | FBP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28568320 | 0.80 | FBP1 (0.50) | FBP1ALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047119-B1 | CARBOXAMIDE COMPOUNDS AS SRS-A ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THE PREPARATION, AND INTERMEDIATES USEFUL THEREIN | PFIZER INC. (US) | 1984-05-09 | — | — | EP | disclosed |
| EP-0050977-B1 | CARBOXAMIDE COMPOUNDS AS SRS-A ANTAGONISTS AND A PROCESS FOR PRODUCING SAME | PFIZER INC. (US) | 1983-09-14 | — | — | EP | disclosed |
| US-4343813-A | ANTIANAPHYLACTIC AGENTS | PFIZER INC. (US) | 1982-08-10 | — | — | US | disclosed |
| US-4331683-A | SENSITIZATION, ANTIALLERGENS | PFIZER INC. (US) | 1982-05-25 | — | — | US | disclosed |
| EP-0050977-A1 | Carboxamide compounds as SRS-A antagonists and a process for producing same | PFIZER INC. (US) | 1982-05-05 | — | — | EP | disclosed |
| EP-0047119-A1 | Carboxamide compounds as SRS-A antagonists, pharmaceutical compositions containing them, processes for the preparation, and intermediates useful therein | PFIZER INC. (US) | 1982-03-10 | — | — | EP | disclosed |
| US-4296120-A | ANTIANAPHYLACTIC | PFIZER INC. (US) | 1981-10-20 | — | — | US | disclosed |
| US-4296129-A | ANTIAASTHMATIC INHIBITOR OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS | PFIZER, INC. (US) | 1981-10-20 | — | — | US | disclosed |
| US-4182897-A | ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES | TORII & CO., LTD. (JP) | 1980-01-08 | — | — | US | disclosed |