Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 10/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100149 | 0.84 | TBK1 (0.46) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11107442 | 0.82 | TBK1 (0.51) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11096969 | 0.82 | TBK1 (0.46) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11099326 | 0.82 | TBK1 (0.53) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11125444 | 0.81 | TBK1 (0.47) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11394403 | 0.80 | TBK1 (0.44) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11101367 | 0.78 | TBK1 (0.42) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11098818 | 0.77 | RAB9A (0.44) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11356803 | 0.75 | TBK1 (0.44) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11102021 | 0.73 | TBK1 (0.53) | TBK1IKBKEKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026675-B1 | 1-AZAXANTHONE-3-CARBOXYLIC ACIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4302463-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-24 | — | — | US | disclosed |