Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 12/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100149 | 0.86 | TBK1 (0.46) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11096969 | 0.86 | TBK1 (0.46) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11367261 | 0.84 | NT5E (0.45) | NPC1RAB9AKDM4EPKMMAPT | |
| SCHEMBL6206524 | 0.84 | TBK1 (0.65) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11101370 | 0.82 | TBK1 (0.42) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11375422 | 0.82 | GPR35 (0.46) | NPC1RAB9AKDM4ETTRGAA | |
| SCHEMBL11101367 | 0.81 | TBK1 (0.42) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11375110 | 0.81 | TBK1 (0.48) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11354192 | 0.81 | TBK1 (0.37) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL2901850 | 0.79 | TBK1 (0.72) | TBK1IKBKENPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | claimed |
| EP-0026675-B1 | 1-AZAXANTHONE-3-CARBOXYLIC ACIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4302463-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-24 | — | — | US | disclosed |
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4267332-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
| EP-0026675-A1 | 1-Azaxanthone-3-carboxylic acids, their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1981-04-08 | — | — | EP | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | disclosed |