SCHEMBL11101385

SCHEMBL11101385

CCCCN(c1nc(NCCO)nc(NCCO)n1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
SLC29A1 Q99808 3/20 0.39
GBA1 P04062 2/20 0.34
MAPK1 P28482 2/20 0.32
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9091458 0.98 SLC29A1 (0.39) KMT2ASLC29A1GBA1MAPK1MEN1
SCHEMBL9861690 0.94 KMT2A (0.37) KMT2ASLC29A1GBA1
SCHEMBL9091672 0.92 SLC29A1 (0.35) KMT2ASLC29A1
SCHEMBL3136072 0.89 SLC29A1 (0.33) SLC29A1
SCHEMBL15961463 0.89 ESR1 (0.32) KMT2AMEN1
SCHEMBL10167577 0.88 NPY1R (0.33) KMT2ASLC29A1
SCHEMBL9367814 0.88 DNM2 (0.34) KMT2A
SCHEMBL11338890 0.88 SLC29A1 (0.33) KMT2ASLC29A1MAPK1
SCHEMBL11426398 0.88 GAA (0.38) KMT2AMEN1GAAALDH1A1
SCHEMBL10910189 0.88 KMT2A (0.38) KMT2ASLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4476302-A PHOTOSTABILITY HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-09 US disclosed
EP-0061659-A1 Piperidine groups containing esters,methods for their preparation, their use as stabilising agents for polymers, and polymers containing these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-06 EP disclosed