Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109213 | 0.86 | THRB (0.44) | THRBTDP1MAPTAPEX1GLA | |
| SCHEMBL16345537 | 0.85 | ROCK2 (0.46) | — | |
| SCHEMBL11107251 | 0.76 | MAPT (0.42) | MAPTGLACTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11105120 | 0.76 | THRB (0.47) | THRBTDP1MAPTAPEX1GLA | |
| SCHEMBL11105045 | 0.74 | APEX1 (0.53) | THRBTDP1MAPTAPEX1GLA | |
| SCHEMBL11111238 | 0.72 | AKR1B1 (0.43) | THRBTDP1MAPTAPEX1GLA | |
| SCHEMBL11109835 | 0.71 | TDP1 (0.46) | THRBTDP1MAPTAPEX1GLA | |
| SCHEMBL11104839 | 0.71 | THRB (0.39) | THRBTDP1MAPTAPEX1GLA | |
| SCHEMBL11108558 | 0.70 | APEX1 (0.55) | THRBTDP1MAPTAPEX1GLA | |
| SCHEMBL11105945 | 0.69 | LMNA (0.41) | MAPTGLACTDSP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |