Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 5/20 | 0.52 |
| ▸ | ATP4B | P51164 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105051 | 0.86 | ATP4A (0.63) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL11104476 | 0.86 | ATP4A (0.50) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL11109084 | 0.84 | ATP4A (0.48) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL11101851 | 0.82 | ATP4A (0.66) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL11113214 | 0.80 | ATP4A (0.48) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL11107761 | 0.78 | LTA4H (0.50) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL2193469 | 0.76 | ATP4A (0.76) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL11106437 | 0.72 | MAPK14 (0.45) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL10918911 | 0.69 | ATP4A (0.76) | ATP4AATP4BCYP1A2MAPK1CYP3A4 | |
| SCHEMBL8816284 | 0.69 | ATP4A (0.74) | ATP4AATP4BCYP1A2MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464372-A | ANTIULCER | SCHERING CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |