Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 4/20 | 0.48 |
| ▸ | ATP4B | P51164 | 4/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107482 | 0.80 | ATP4A (0.52) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL25151340 | 0.78 | STAT3 (0.47) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL5212872 | 0.74 | ATP4A (0.52) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL5034255 | 0.73 | ATP4A (0.51) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL5216426 | 0.73 | ATP4A (0.58) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL2193469 | 0.72 | ATP4A (0.76) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL4591666 | 0.71 | ATP4A (0.50) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL9134502 | 0.70 | HTT (0.54) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL5381408 | 0.69 | SMN1; SMN2 (0.54) | STAT3HTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL21636964 | 0.69 | HTT (0.44) | ATP4AATP4BSTAT3HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464372-A | ANTIULCER | SCHERING CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |