Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109355 | 0.88 | MEN1 (0.43) | PPIAATMHSD17B1HSD17B2MEN1 | |
| SCHEMBL11104414 | 0.82 | PPIA (0.38) | PPIAATMKMT2AMAPTALDH1A1 | |
| SCHEMBL11112299 | 0.81 | ALDH1A1 (0.51) | PPIAATMMEN1KMT2ACYP1A2 | |
| SCHEMBL11113554 | 0.80 | ATM (0.49) | ATMMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL11105851 | 0.80 | AR (0.46) | PPIAATMMAPTALDH1A1 | |
| SCHEMBL11108397 | 0.79 | PPIA (0.40) | PPIAATMHSD17B1HSD17B2MEN1 | |
| SCHEMBL11101143 | 0.77 | PPIA (0.42) | PPIAATMHSD17B1HSD17B2MEN1 | |
| SCHEMBL11106295 | 0.77 | APEX1 (0.43) | PPIAATMHSD17B1HSD17B2MEN1 | |
| SCHEMBL11104927 | 0.77 | CYP1A2 (0.45) | PPIAATMMEN1KMT2ACYP1A2 | |
| SCHEMBL11108838 | 0.76 | ALDH1A1 (0.47) | ATMMEN1KMT2ASIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |