Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.61 |
| ▸ | LTA4H | P09960 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16114401 | 0.89 | LMNA (0.75) | LMNATDP1CYP19A1LTA4HCYP11B1 | |
| SCHEMBL27062127 | 0.86 | LMNA (0.71) | LMNATDP1CYP19A1LTA4HKMT2A | |
| SCHEMBL29742666 | 0.86 | LMNA (0.71) | LMNATDP1CYP19A1LTA4HKMT2A | |
| SCHEMBL27968872 | 0.85 | LMNA (0.69) | LMNATDP1CYP19A1LTA4HCYP11B1 | |
| SCHEMBL29441943 | 0.85 | — | — | |
| SCHEMBL162478 | 0.85 | — | — | |
| SCHEMBL30535283 | 0.85 | LMNA (0.82) | LMNATDP1CYP19A1LTA4HCYP11B1 | |
| SCHEMBL676142 | 0.85 | LMNA (0.82) | LMNATDP1CYP19A1LTA4HCYP11B1 | |
| SCHEMBL11457992 | 0.85 | LMNA (0.81) | LMNATDP1CYP19A1KMT2ACYP11B1 | |
| SCHEMBL169035 | 0.84 | LMNA (0.62) | LMNATDP1CYP19A1LTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146518-A | A kind of bruton's tyrosine kinase inhibitor intermediate and preparation method thereof | 苏州爱玛特生物科技有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-4455427-A | THROMBOXANE INHIBITORS | THE UPJOHN COMPANY (US) | 1984-06-19 | — | — | US | disclosed |
| EP-0069521-A2 | Pyridinyl and imidazolyl derivatives of benzofurans and benzothiophenes | THE UPJOHN COMPANY (US) | 1983-01-12 | — | — | EP | disclosed |