Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.67 |
| ▸ | LTA4H | P09960 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78141 | 0.98 | LMNA (0.72) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL29500180 | 0.98 | LMNA (0.72) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| Bromide SCHEMBL9391382 | 0.95 | LMNA (0.69) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL9386460 | 0.95 | LMNA (0.69) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL16114401 | 0.95 | LMNA (0.75) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL30535283 | 0.91 | LMNA (0.82) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL676142 | 0.91 | LMNA (0.82) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| Potassium SCHEMBL6776357 | 0.88 | LMNA (0.78) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| Sulfuric Acid SCHEMBL11641651 | 0.86 | TDP1 (0.58) | LMNATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6510014 | 0.86 | TDP1 (0.58) | LMNATDP1CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103814016-B | Compositions and methods for producing pyrimidine and pyridine compounds having BTK inhibitory activity | 默克专利有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-103814016-A | Compositions and methods for producing pyrimidine and pyridine compounds having BTK inhibitory activity | MERCK PATENT GMBH | 2014-05-21 | — | — | CN | disclosed |