Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.50 |
| ▸ | MMP14 | P50281 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768369 | 0.86 | KDM4E (0.66) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10908982 | 0.72 | MEN1 (0.64) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6051170 | 0.70 | KDM4E (0.77) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| Clioquinol SCHEMBL4460424 | 0.70 | HSP90AA1 (0.78) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| Clioquinol SCHEMBL15476935 | 0.69 | MEN1 (0.76) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| Chloroxine SCHEMBL3350 | 0.69 | KDM4E (1.00) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| Chloroxine SCHEMBL29389908 | 0.69 | KDM4E (1.00) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| Chloroxine SCHEMBL29399997 | 0.69 | KDM4E (1.00) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| Clioquinol SCHEMBL4460420 | 0.68 | KDM4E (0.85) | HSP90AA1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4980639 | 0.68 | KDM4E (0.72) | HSP90AA1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3056509-A1 | BOMBESIN ANALOGUES FOR USE IN DIAGNOSIS | Piramal Imaging SA (CH) | 2016-08-17 | — | — | EP | disclosed |
| EP-2455105-B1 | Bombesin analogues | PIRAMAL IMAGING SA (CH) | 2016-02-17 | — | — | EP | disclosed |
| EP-2063918-B1 | COMPOUNDS AND METHODS FOR 18F LABELED AGENTS | PIRAMAL IMAGING SA (CH) | 2014-02-26 | — | — | EP | disclosed |
| US-8557776-B2 | Compounds and methods for 18F labeled agents | Bayer Pharma AG (DE) | 2013-10-15 | — | — | US | disclosed |
| EP-2455105-A2 | Bombesin analogues | Bayer Pharma Aktiengesellschaft (DE) | 2012-05-23 | — | — | EP | disclosed |
| EP-2289564-A2 | Derivatives of aniline as precursors for F18-labeling | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-03-02 | — | — | EP | disclosed |
| EP-2279759-A2 | Compounds and methods for 18F labeled agents | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-02-02 | — | — | EP | disclosed |
| EP-2146753-A2 | 18F FLUORO-BENZOYL LABELLED BIOLOGICAL ACTIVE COMPOUNDS AS DIAGNOSTIC IMAGING AGENTS AS WELL AS BENZOTRIAZOL-1-YLOXY-BENZOYL , 2,5-DIOXO-PYRROLIDIN-1-YLOXY)BENZOYL AND TRIMETHYLAMMONIO-BENZOYL PRECURSERS THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-01-27 | — | — | EP | disclosed |
| US-20090317326-A1 | RADIOFLUORINATION METHODS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-12-24 | — | — | US | disclosed |
| EP-2063918-A2 | COMPOUNDS AND METHODS FOR 18F LABELED AGENTS | Bayer Schering Pharma AG (DE) | 2009-06-03 | — | — | EP | disclosed |
| US-20080292548-A1 | COMPOUNDS AND METHODS FOR 18F LABELED AGENTS | Lantheus Biosciences Ltd. (GB) | 2008-11-27 | — | — | US | disclosed |
| WO-2008104203-A2 | 18F FLUORO-BENZOYL LABELLED BIOLOGICAL ACTIVE COUMPOUNDS AS DIAGNOSITIC IMAGING AGENTS AS WELL AS BENZOTRIAZOL-1-YLOXY-BENZOYL, 2,5-DIOXO-PYRROLIDIN-1-YLOXY) BENZOYL AND TRIMETHYLAMMONIO-BENZOYL PRECURSERS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | WO | disclosed |
| EP-1964848-A1 | Radiofluorination methods | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| WO-2008028688-A2 | COMPOUNDS AND METHODS FOR 18F LABELED AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |
| EP-1897885-A1 | Compounds and methods for F labelled agents | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292548-A1 | COMPOUNDS AND METHODS FOR 18F LABELED AGENTS | QPCT, GBA2, GBA1 | HSP90AA1 3875/4885MEN1 56/4885KMT2A 2260/4885 |
| US-20090317326-A1 | RADIOFLUORINATION METHODS | CDC73, TMEM14C, FLI1 | HSP90AA1 3368/4885MEN1 1071/4885KMT2A 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.