Chloroxine

Chloroxine

SCHEMBL29389908

Oc1c(Cl)cc(Cl)c2cccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 1.00
▸ HSP90AA1 P07900 7/20 1.00
▸ MEN1 O00255 6/20 1.00
▸ HTT P42858 6/20 1.00
▸ KMT2A Q03164 6/20 1.00
▸ SMN1; SMN2 Q16637 6/20 1.00
▸ TDP1 Q9NUW8 6/20 1.00
▸ MAPT P10636 5/20 1.00
▸ LMNA P02545 5/20 1.00
▸ ALDH1A1 P00352 4/20 1.00
▸ TP53 P04637 4/20 1.00
▸ MMP14 P50281 3/20 1.00
▸ OPRK1 P41145 3/20 1.00
▸ ALOX15 P16050 3/20 1.00
▸ SLC6A2 P23975 3/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ ALOX12 P18054 2/20 1.00
▸ ALOX15B O15296 1/20 1.00
▸ NR1I2 O75469 1/20 1.00
▸ HTR1A P08908 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroxine SCHEMBL29399997 1.00 KDM4E (1.00) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL3350 1.00 KDM4E (1.00) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL231205 0.98 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL22734873 0.98 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL4297732 0.98 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL9135479 0.98 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL4293183 0.98 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL6677225 0.98 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL31016232 0.98 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A
Chloroxine SCHEMBL28905314 0.98 KDM4E (0.96) KDM4EHSP90AA1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119770427-A Haquinolone suspension and preparation method thereof 郑州原理生物科技有限公司 2025-04-08 — — CN claimed
CN-118344408-A Nitrosyl ruthenium complex with hydroxyproline and 5, 7-dichloro-8-hydroxyquinoline as ligands, and preparation method and application thereof 山西大学 2024-07-16 — — CN claimed
CN-118206588-A 8-Hydroxyquinoline-triphenylphosphine rhodium (III) complex, synthesis method and application thereof 玉林师范学院 2024-06-18 — — CN claimed
CN-117402494-A Complex high-strength polyarylene sulfide based composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-01-16 — — CN claimed
CN-116789683-A 8-hydroxyquinoline anticancer zinc (II) complex and synthetic method and application thereof 玉林师范学院 2023-09-22 — — CN claimed
CN-116789684-A 8-hydroxyquinoline anticancer zinc (II) complex and synthetic method and application thereof 玉林师范学院 2023-09-22 — — CN claimed
CN-114621753-A Cyan fluorescent material prepared from aluminum complex and preparation method thereof 青岛大学 2022-06-14 — — CN claimed
CN-113683644-B Bis-quinoline iridium complex for treating cisplatin-resistant cancer cells and preparation method and application thereof 玉林师范学院 2022-05-20 — — CN claimed
CN-116789684-B 8-Hydroxyquinoline anticancer zinc (II) complex and synthetic method and application thereof 玉林师范学院 2026-02-17 — — CN disclosed
CN-121202925-A 8-Hydroxyquinoline platinum complex as well as preparation method and application thereof 玉林师范学院 2025-12-26 — — CN disclosed
CN-116789683-B 8-Hydroxyquinoline anticancer zinc (II) complex and synthetic method and application thereof 玉林师范学院 2025-12-19 — — CN disclosed
CN-119770427-A Haquinolone suspension and preparation method thereof 郑州原理生物科技有限公司 2025-04-08 — — CN disclosed
US-20240285552-A1 COMPOSITIONS FOR AND METHODS OF INHIBITING SARS-COV-2 INFECTION TEXAS SOUTHERN UNIVERSITY (US) 2024-08-29 — — US disclosed
CN-118344408-A Nitrosyl ruthenium complex with hydroxyproline and 5, 7-dichloro-8-hydroxyquinoline as ligands, and preparation method and application thereof 山西大学 2024-07-16 — — CN disclosed
WO-2022187683-A1 LOADING OF ALGINATE MICROSPHERES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-09-09 — — WO disclosed
CN-108950247-B Extraction system and application thereof 中国科学院上海有机化学研究所 2022-07-19 — — CN disclosed
CN-114621753-A Cyan fluorescent material prepared from aluminum complex and preparation method thereof 青岛大学 2022-06-14 — — CN disclosed
CN-113683644-B Bis-quinoline iridium complex for treating cisplatin-resistant cancer cells and preparation method and application thereof 玉林师范学院 2022-05-20 — — CN disclosed
CN-108191753-B Preparation method of 5-chloro-8-hydroxyquinoline 利尔化学股份有限公司 2022-03-15 — — CN disclosed
WO-2022036272-A1 COMPOSITIONS FOR AND METHODS OF INHIBITING SARS-COV2 INFECTION TEXAS SOUTHERN UNIVERSITY (US) 2022-02-17 — — WO disclosed
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