Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103349 | 1.00 | HTR1A (0.48) | HTR1ADRD2DRD4 | |
| SCHEMBL11105438 | 0.97 | HTR1A (0.48) | HTR1ADRD2DRD4 | |
| Maleic Acid SCHEMBL11112010 | 0.90 | HTR1A (0.43) | HTR1ADRD2DRD4 | |
| SCHEMBL10817359 | 0.87 | ALDH1A1 (0.62) | — | |
| SCHEMBL11105790 | 0.87 | ALDH1A1 (0.62) | — | |
| SCHEMBL11109339 | 0.84 | ALDH1A1 (0.59) | — | |
| SCHEMBL11112996 | 0.84 | ALDH1A1 (0.59) | — | |
| SCHEMBL11107130 | 0.82 | ALDH1A1 (0.56) | HTR1ADRD2 | |
| SCHEMBL11102748 | 0.82 | DRD2 (0.43) | HTR1ADRD2DRD4 | |
| SCHEMBL11106525 | 0.81 | HTR1A (0.53) | HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479954-A | ANTIDIABETIC AGENTS | EISAI CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |