Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104445 | 0.82 | KDM4E (0.44) | LCKFYNPKMHPGDALDH1A1 | |
| SCHEMBL7911729 | 0.79 | CYP1A1 (0.58) | HPGDALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL503977 | 0.77 | GAA (0.65) | MCL1HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL10373746 | 0.77 | MCL1 (0.61) | LCKFYNMCL1HPGDALDH1A1 | |
| SCHEMBL1613893 | 0.77 | TPMT (0.68) | LCKFYNPKMHPGDALDH1A1 | |
| SCHEMBL8554349 | 0.77 | MAPT (0.63) | LCKFYNPKMMCL1HPGD | |
| SCHEMBL10355461 | 0.77 | ACHE (0.59) | LCKFYNPKMMCL1HPGD | |
| SCHEMBL4847814 | 0.77 | KDM4E (0.53) | LCKFYNPKMHPGDALDH1A1 | |
| SCHEMBL1438926 | 0.76 | PKM (0.62) | LCKFYNPKMHPGDALDH1A1 | |
| SCHEMBL9787558 | 0.75 | PKM (0.49) | LCKFYNPKMHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434170-A | NEUROLEPTIC AGENTS, ANTIEMETICS, LAXATIVES | DELALANDE S.A. (FR) | 1984-02-28 | — | — | US | disclosed |