Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109198 | 0.82 | LCK (0.47) | KDM4EALDH1A1PKMTDP1LCK | |
| SCHEMBL8351063 | 0.81 | PTGS2 (0.54) | ALDH1A1PKMTDP1MAPT | |
| SCHEMBL11768114 | 0.79 | ALDH1A1 (0.54) | KDM4EALDH1A1TDP1LCKFYN | |
| SCHEMBL10355749 | 0.76 | PTGS2 (0.63) | KDM4EALDH1A1PKMTDP1LCK | |
| SCHEMBL8555013 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1PKMHPGDMAPT | |
| SCHEMBL4847814 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1PKMTDP1LCK | |
| SCHEMBL1613893 | 0.73 | TPMT (0.68) | KDM4EALDH1A1PKMTDP1LCK | |
| SCHEMBL10355461 | 0.73 | ACHE (0.59) | KDM4EALDH1A1PKMTDP1LCK | |
| SCHEMBL8554349 | 0.73 | MAPT (0.63) | KDM4EALDH1A1PKMTDP1LCK | |
| SCHEMBL1438926 | 0.72 | PKM (0.62) | KDM4EALDH1A1PKMTDP1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434170-A | NEUROLEPTIC AGENTS, ANTIEMETICS, LAXATIVES | DELALANDE S.A. (FR) | 1984-02-28 | — | — | US | disclosed |