Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105495 | 0.83 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL11104368 | 0.81 | GALR3 (0.57) | EGFRLMNA | |
| SCHEMBL11281906 | 0.77 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL11105703 | 0.74 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL4572186 | 0.72 | RPS6KB1 (0.53) | EGFRRPS6KB1LMNAP2RX3 | |
| SCHEMBL4572192 | 0.72 | RPS6KB1 (0.53) | EGFRRPS6KB1LMNAP2RX3 | |
| SCHEMBL11108426 | 0.72 | MAOA (0.48) | LMNA | |
| SCHEMBL3952919 | 0.71 | EGFR (0.49) | EGFRRPS6KB1CRHR1 | |
| SCHEMBL11105507 | 0.71 | AKT1 (0.44) | EGFRRPS6KB1LMNAP2RX3 | |
| SCHEMBL11286075 | 0.71 | EGFR (0.46) | EGFRRPS6KB1LMNAP2RX3CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |