SCHEMBL11110059

SCHEMBL11110059

CCCCCOC(=O)Oc1cc([N+](=O)[O-])c2c(c1N)C(=O)c1ccccc1C2=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.48
ESR1 P03372 1/20 0.41
POLB P06746 2/20 0.39
MAPT P10636 2/20 0.39
APEX1 P27695 1/20 0.39
CASP6 P55212 1/20 0.39
PTPN1 P18031 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
CACNA1F O60840 1/20 0.37
CACNA1D Q01668 1/20 0.37
CACNA1S Q13698 1/20 0.37
CACNA1C Q13936 1/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10890113 0.84 ALDH1A1 (0.48) ESR1POLBMAPTAPEX1CASP6
SCHEMBL10606221 0.82 MGLL (0.48)
SCHEMBL11115398 0.80 MAPT (0.44) POLBMAPTAPEX1CASP6PTPN1
SCHEMBL10696752 0.79 MAPT (0.48) POLBMAPTAPEX1CASP6PTPN1
SCHEMBL3375833 0.79 MAPT (0.48) POLBMAPTAPEX1CASP6PTPN1
SCHEMBL10607101 0.78 MAPT (0.47) POLBMAPTAPEX1CASP6PTPN1
SCHEMBL11113989 0.77 ALDH1A1 (0.44) POLBMAPTAPEX1CASP6L3MBTL1
SCHEMBL10607346 0.76 ALDH1A1 (0.41) POLBMAPTAPEX1CASP6L3MBTL1
SCHEMBL27131470 0.76 L3MBTL1 (0.55) ELANEESR1MAPTL3MBTL1ALDH1A1
SCHEMBL9816486 0.73 POLB (0.38) POLBMAPTAPEX1CASP6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0111197-A2 Anthraquinone dyes, their preparation and use, as well as dichroic material containing anthraquinone dyes BAYER AG (DE) 1984-06-20 EP disclosed