Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 8/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115519 | 0.81 | P2RX4 (0.47) | P2RX4P2RX1P2RX3P2RX7PTBP1 | |
| SCHEMBL11108291 | 0.79 | BCHE (0.54) | P2RX4NPSR1BCHEPOLBGAA | |
| SCHEMBL4458688 | 0.76 | P2RX4 (0.43) | P2RX4P2RX1P2RX3P2RX7PTBP1 | |
| SCHEMBL1572434 | 0.76 | P2RX4 (0.62) | P2RX4P2RX1P2RX3P2RX7BCHE | |
| SCHEMBL1572458 | 0.76 | LMNA (0.54) | P2RX4P2RX1P2RX3P2RX7BCHE | |
| SCHEMBL11118498 | 0.74 | BCHE (0.47) | P2RX4P2RX1P2RX3P2RX7SMN1; SMN2 | |
| SCHEMBL11113107 | 0.71 | ALDH1A1 (0.56) | P2RX4P2RX1P2RX3P2RX7PTBP1 | |
| SCHEMBL15871613 | 0.70 | CDC25A (0.51) | CES1 | |
| SCHEMBL1572427 | 0.69 | P2RX4 (0.56) | P2RX4P2RX1P2RX3P2RX7PTBP1 | |
| SCHEMBL24119510 | 0.69 | ALDH1A1 (0.48) | P2RX4P2RX1P2RX3SMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | claimed |
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |