Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 9/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572434 | 0.85 | P2RX4 (0.62) | P2RX4GPR84PTPN1CES1LMNA | |
| SCHEMBL1572458 | 0.85 | LMNA (0.54) | P2RX4GPR84PTPN1CES1LMNA | |
| SCHEMBL11115519 | 0.83 | P2RX4 (0.47) | P2RX4GPR84PTPN1CES1LMNA | |
| SCHEMBL11118498 | 0.83 | BCHE (0.47) | P2RX4GPR84PTPN1CES1LMNA | |
| SCHEMBL11113522 | 0.80 | P2RX4 (0.45) | P2RX4GPR84CES1LMNATSHR | |
| SCHEMBL14305634 | 0.78 | P2RX4 (0.46) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL11622785 | 0.77 | P2RX4 (0.45) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL13030142 | 0.77 | P2RX4 (0.38) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11108291 | 0.76 | BCHE (0.54) | P2RX4TSHRALDH1A1NPSR1BCHE | |
| SCHEMBL11110072 | 0.76 | P2RX4 (0.54) | P2RX4CES1P2RX1P2RX3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032647-A1 | Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride | AMOLI ORGANICS LTD. (IN) | 2007-02-08 | — | — | US | claimed |
| EP-1678140-A2 | NOVEL PROCESS FOR PREPARATION OF 10-OXO-10, 11-DIHYDRO-5H-DIBENZ [B,F]AZEPINE-5-CARBOXAMIDE (OXCARBAZEPINE) VIA INTERMEDIATE, 10-METHOXY-5H-DIBENZ [B,F] AZEPINE-5-CARBONYLCHLORIDE | Amoli Organics Ltd. (IN) | 2006-07-12 | — | — | EP | claimed |
| WO-2005066133-A2 | NOVEL PROCESS FOR PREPARATION OF 10-OXO-10, 11-DIHYDRO-5H-DIBENZ [b,f]AZEPINE-5-CARBOXAMIDE (OXCARBAZEPINE) VIA INTERMEDIATE, 10-METHOXY-5H-DIBENZ[b,f] AZEPINE-5-CARBONYLCHLORIDE | AMOLI ORGANICS LTD. (IN) | 2005-07-21 | — | — | WO | claimed |
| US-20210395231-A1 | RECEPTOR INHIBITORS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2021-12-23 | — | — | US | disclosed |
| EP-3760620-A1 | RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USAGE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| WO-2019161781-A1 | RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USAGE THEREOF | 北京泰德制药股份有限公司 | 2019-08-29 | — | — | WO | disclosed |
| US-8530647-B2 | Process for the preparation of oxcarbazepine | MYLAN LABORATORIES LIMITED (IN) | 2013-09-10 | — | — | US | disclosed |
| US-20110065917-A1 | PROCESS FOR THE PREPARATION OF OXCARBAZEPINE | MATRIX LABORATORIES LTD (IN) | 2011-03-17 | — | — | US | disclosed |
| US-7858779-B2 | Process for preparing oxcarbazepine | ARCHIMICA S.R.L. (IT) | 2010-12-28 | — | — | US | disclosed |
| US-7858779-B2 | Process for preparing oxcarbazepine | ARCHIMICA S.R.L. (IT) | 2010-12-28 | — | — | US | disclosed |
| EP-1758867-B1 | PROCESS FOR PREPARING OXCARBAZEPINE | ARCHIMICA SRL (IT) | 2010-09-29 | — | — | EP | disclosed |
| US-20070149507-A1 | chlorocarbonylating, ammonolysis, and deprotecting; using triphosgene; without using corrosive reagents such as phosgene | ARCHIMICA S.R.L. (IT) | 2007-06-28 | — | — | US | disclosed |
| US-20070149507-A1 | chlorocarbonylating, ammonolysis, and deprotecting; using triphosgene; without using corrosive reagents such as phosgene | ARCHIMICA S.R.L. (IT) | 2007-06-28 | — | — | US | disclosed |
| US-20070032647-A1 | Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride | AMOLI ORGANICS LTD. (IN) | 2007-02-08 | — | — | US | disclosed |
| US-20070032647-A1 | Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride | AMOLI ORGANICS LTD. (IN) | 2007-02-08 | — | — | US | disclosed |
| US-20070032647-A1 | Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride | AMOLI ORGANICS LTD. (IN) | 2007-02-08 | — | — | US | disclosed |
| US-20070032647-A1 | Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride | AMOLI ORGANICS LTD. (IN) | 2007-02-08 | — | — | US | disclosed |
| US-20060166968-A1 | Crystalline form of oxcarbazepine | DR. REDDY'S LABORATORIES, INC. | 2006-07-27 | — | — | US | disclosed |
| EP-1678140-A2 | NOVEL PROCESS FOR PREPARATION OF 10-OXO-10, 11-DIHYDRO-5H-DIBENZ [B,F]AZEPINE-5-CARBOXAMIDE (OXCARBAZEPINE) VIA INTERMEDIATE, 10-METHOXY-5H-DIBENZ [B,F] AZEPINE-5-CARBONYLCHLORIDE | Amoli Organics Ltd. (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005066133-A2 | NOVEL PROCESS FOR PREPARATION OF 10-OXO-10, 11-DIHYDRO-5H-DIBENZ [b,f]AZEPINE-5-CARBOXAMIDE (OXCARBAZEPINE) VIA INTERMEDIATE, 10-METHOXY-5H-DIBENZ[b,f] AZEPINE-5-CARBONYLCHLORIDE | AMOLI ORGANICS LTD. (IN) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395231-A1 | RECEPTOR INHIBITORS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USE THEREOF | TACR1, TACR2, GPBAR1 | P2RX4 138/4885GPR84 25/4885PTPN1 450/4885 |
| US-20070149507-A1 | chlorocarbonylating, ammonolysis, and deprotecting; using triphosgene; without using corrosive reagents such as phosgene | CA3, CTSG, PSEN2 | P2RX4 2484/4885GPR84 3386/4885PTPN1 4230/4885 |
| US-20060166968-A1 | Crystalline form of oxcarbazepine | CACNA1B, CACNA1C, CACNB4 | P2RX4 3974/4885GPR84 2988/4885PTPN1 4597/4885 |
| US-20110065917-A1 | PROCESS FOR THE PREPARATION OF OXCARBAZEPINE | CYP8B1, CYP4F12, CYP2F1 | P2RX4 2052/4885GPR84 1343/4885PTPN1 4849/4885 |
| US-20070032647-A1 | Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride | BRD9, KCNMB1, BTD | P2RX4 3627/4885GPR84 1433/4885PTPN1 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.