SCHEMBL1111008

SCHEMBL1111008

CCCCCCCCCCCC(CC1CC(C)O1)OC(CCCCCCCCCCC)CC1CC(C)O1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ EBP Q15125 1/20 0.39
▸ SIGMAR1 Q99720 1/20 0.39
▸ LMNA P02545 1/20 0.33
▸ ALDH1A1 P00352 3/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ PDCD4 Q53EL6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10490360 1.00 EBP (0.39) EBPSIGMAR1LMNAALDH1A1TDP1
SCHEMBL1110951 0.85 ALDH1A1 (0.43) EBPSIGMAR1ALDH1A1
SCHEMBL5972212 0.85 ALDH1A1 (0.39) EBPSIGMAR1ALDH1A1
SCHEMBL18662303 0.85 EBP (0.38) EBPSIGMAR1ALDH1A1TDP1
SCHEMBL1110980 0.85 ALDH1A1 (0.43) EBPSIGMAR1ALDH1A1
SCHEMBL2049944 0.85 ALDH1A1 (0.43) EBPSIGMAR1ALDH1A1
SCHEMBL18662315 0.85 ALDH1A1 (0.43) EBPSIGMAR1ALDH1A1
SCHEMBL29593 0.81 ALDH1A1 (0.48) LMNAALDH1A1TDP1PDCD4
SCHEMBL3245975 0.81 ALDH1A1 (0.48) LMNAALDH1A1TDP1PDCD4
SCHEMBL3241159 0.81 ALDH1A1 (0.48) LMNAALDH1A1TDP1PDCD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230398131-A1 PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND CORTICOSTEROID LEO PHARMA AS (DK) 2023-12-14 — — US claimed
CN-114555055-A Anhydrous pharmaceutical composition for the maintenance treatment of psoriasis 利奥制药有限公司 2022-05-27 — — CN claimed
US-20210128588-A1 PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND CORTICOSTEROID LEO PHARMA A/S 2021-05-06 — — US claimed
WO-2021069496-A1 AN ANHYDROUS PHARMACEUTICAL COMPOSITION FOR MAINTENANCE TREATMENT OF PSORIASIS LEO PHARMA A/S (DK) 2021-04-15 — — WO claimed
US-10716799-B2 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid LEO PHARMA A/S (DK) 2020-07-21 — — US claimed
US-10682364-B2 Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid LEO PHARMA A/S (DK) 2020-06-16 — — US claimed
US-10660908-B2 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid LEO PHARMA A/S (DK) 2020-05-26 — — US claimed
US-10617698-B2 Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid LEO PHARMA A/S (DK) 2020-04-14 — — US claimed
US-20190015430-A1 PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND A CORTICOSTEROID LEO PHARMA A/S (DK) 2019-01-17 — — US claimed
US-10130640-B2 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid LEO PHARMA A/S (DK) 2018-11-20 — — US claimed
WO-2011076209-A2 PHARMACEUTICAL COMPOSITION COMPRISING SOLVENT MIXTURE AND A VITAMIN D DERIVATIVE OR ANALOGUE LEO PHARMA A/S (DK) 2011-06-30 — — WO claimed
CN-101987070-A Oil-in-water microemulsion with high oil-loading quantity EVONIK DEGUSSA CHINA CO LTD 2011-03-23 — — CN claimed
CN-101987069-A Thermally stable oil-in-water microemulsion EVONIK DEGUSSA CHINA CO LTD 2011-03-23 — — CN claimed
US-20110028424-A1 OIL-IN-WATER MICROEMULSION CARRYING LARGE AMOUNT OF OIL EVONIK GOLDSCHMIDT GMBH (DE) 2011-02-03 — — US claimed
EP-2279724-A2 Oil-in-water microemulsion carrying large amount of oil Evonik Goldschmidt GmbH (DE) 2011-02-02 — — EP claimed
US-7622844-B1 Metal fiber brush interface conditioning HIPERCON, LLC (US) 2009-11-24 — — US claimed
EP-1255528-B1 LOW TACK COSMETIC COMPOSITION STICKS COLGATE PALMOLIVE CO (US) 2005-11-16 — — EP claimed
EP-1255528-A1 LOW TACK COSMETIC COMPOSITION STICKS Colgate-Palmolive Company (US) 2002-11-13 — — EP claimed
WO-2001060329-A1 LOW TACK COSMETIC COMPOSITION STICKS COLGATE-PALMOLIVE COMPANY (US) 2001-08-23 — — WO claimed
US-6180125-B1 AS ANTIPERSPIRANT COLGATE-PALMOLIVE COMPANY 2001-01-30 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398131-A1 PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND CORTICOSTEROID CYP24A1, CYP2R1, VDR EBP 53/4885SIGMAR1 4511/4885LMNA 3491/4885
US-10716799-B2 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid CYP24A1, CYP2R1, VDR EBP 54/4885SIGMAR1 4515/4885LMNA 3007/4885
US-20190015430-A1 PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND A CORTICOSTEROID CYP24A1, CYP2R1, VDR EBP 54/4885SIGMAR1 4515/4885LMNA 3007/4885
US-20210128588-A1 PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND CORTICOSTEROID CYP24A1, CYP2R1, VDR EBP 53/4885SIGMAR1 4511/4885LMNA 3491/4885
US-10660908-B2 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid CYP24A1, CYP2R1, VDR EBP 54/4885SIGMAR1 4515/4885LMNA 3007/4885
US-10130640-B2 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid CYP24A1, CYP2R1, VDR EBP 49/4885SIGMAR1 4517/4885LMNA 3046/4885
US-10617698-B2 Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid CYP24A1, CYP2R1, VDR EBP 55/4885SIGMAR1 4643/4885LMNA 2948/4885
US-10682364-B2 Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid CYP24A1, CYP2R1, VDR EBP 66/4885SIGMAR1 4508/4885LMNA 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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