Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.73 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | HNF4A | P41235 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070297 | 0.85 | MCL1 (0.72) | MCL1ACMSDDHFRHNF4AHSD11B1 | |
| SCHEMBL18231987 | 0.85 | MCL1 (0.73) | MCL1ACMSDDHFRHNF4ACSNK2A1 | |
| SCHEMBL4967083 | 0.85 | MCL1 (1.00) | MCL1ACMSDDHFRHNF4ACSNK2A1 | |
| SCHEMBL8265893 | 0.84 | ACMSD (0.53) | MCL1ACMSDDHFRHNF4ACSNK2A1 | |
| SCHEMBL29495347 | 0.84 | CSNK2A1 (0.69) | MCL1CSNK2A1LMNATP53HTT | |
| SCHEMBL471440 | 0.84 | CSNK2A1 (0.69) | MCL1CSNK2A1LMNATP53HTT | |
| SCHEMBL17233413 | 0.83 | ALOX5 (0.57) | MCL1ACMSDDHFRHNF4AESR1 | |
| SCHEMBL6559319 | 0.83 | MAOA (0.55) | MCL1ACMSDDHFRHNF4AESR1 | |
| Dimethylamine SCHEMBL1647032 | 0.82 | CSNK2A1 (0.62) | MCL1CSNK2A1NPC1LMNATP53 | |
| SCHEMBL18231986 | 0.82 | MCL1 (0.73) | MCL1ACMSDDHFRHNF4ACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| EP-0000377-B1 | PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |