Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110226 | 0.85 | ACE (0.53) | ACEKMT2AHSD17B10FFAR2ALDH1A1 | |
| SCHEMBL11071522 | 0.83 | KMT2A (0.46) | ACEKMT2AMAOBPTPN1HTT | |
| SCHEMBL11248462 | 0.81 | KMT2A (0.49) | ACEKMT2AHSD17B10FFAR2ALDH1A1 | |
| SCHEMBL11190490 | 0.81 | HTT (0.42) | KMT2AHTTHSD17B10FFAR2 | |
| SCHEMBL11234749 | 0.81 | ACE (0.47) | ACEKMT2AHSD17B10FFAR2ALDH1A1 | |
| SCHEMBL11068373 | 0.80 | KMT2A (0.50) | ACEKMT2AHSD17B10FFAR2ALDH1A1 | |
| SCHEMBL11062257 | 0.76 | ACE (0.55) | ACEKMT2AHTTFFAR2 | |
| SCHEMBL11194364 | 0.76 | ACE (0.52) | ACEKMT2AHSD17B10 | |
| SCHEMBL11065209 | 0.76 | ACE (0.49) | ACEKMT2AHTTFFAR2 | |
| SCHEMBL11169739 | 0.76 | ACE (0.49) | ACEKMT2AHTTFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430344-A | Antihypertensive 4-thiazolidinecarboxylic acids | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-02-07 | — | — | US | claimed |