Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.47 |
| ▸ | KRAS | P01116 | 4/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105125 | 0.85 | EGFR (0.48) | EGFRSOS1KRASP2RX3CA1 | |
| SCHEMBL11103467 | 0.82 | EGFR (0.46) | EGFRSOS1KRASP2RX3CA1 | |
| SCHEMBL11126373 | 0.80 | EGFR (0.48) | EGFRSOS1KRASP2RX3CA1 | |
| SCHEMBL11102880 | 0.79 | GALR3 (0.56) | EGFRSOS1KRAS | |
| SCHEMBL11103785 | 0.75 | EGFR (0.43) | EGFRSOS1KRASP2RX3PIK3CD | |
| SCHEMBL11104469 | 0.75 | EGFR (0.48) | EGFRSOS1KRASP2RX3CA1 | |
| SCHEMBL11109199 | 0.75 | EGFR (0.48) | EGFRSOS1KRASP2RX3CA1 | |
| SCHEMBL11105547 | 0.73 | EGFR (0.37) | EGFRSOS1KRASP2RX3PIK3CD | |
| SCHEMBL11109253 | 0.73 | ALDH1A1 (0.45) | EGFRPIK3CD | |
| SCHEMBL11103473 | 0.72 | EGFR (0.53) | EGFRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |