Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | KRAS | P01116 | 3/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105547 | 0.91 | EGFR (0.37) | EGFRKRASSOS1ALOX15GAA | |
| SCHEMBL11105125 | 0.90 | EGFR (0.48) | EGFRKRASSOS1P2RX3PIK3CD | |
| SCHEMBL11102980 | 0.85 | EGFR (0.43) | EGFRKRASSOS1ALOX15GAA | |
| SCHEMBL11100297 | 0.82 | EGFR (0.47) | EGFRKRASSOS1SMN1; SMN2HSD17B10 | |
| SCHEMBL11109382 | 0.82 | P2RX3 (0.47) | EGFRKRASSOS1P2RX3PIK3CD | |
| SCHEMBL11103467 | 0.79 | EGFR (0.46) | EGFRKRASSOS1P2RX3PIK3CD | |
| SCHEMBL11106600 | 0.78 | PIK3CD (0.39) | EGFRKRASSOS1ALOX15GAA | |
| SCHEMBL11101615 | 0.76 | GALR3 (0.57) | EGFRKRASSOS1SMN1; SMN2HSD17B10 | |
| SCHEMBL11110469 | 0.75 | EGFR (0.47) | EGFRKRASSOS1P2RX3PIK3CD | |
| SCHEMBL11101473 | 0.75 | LMNA (0.43) | EGFRGAAMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |