Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | MMP16 | P51512 | 2/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260400 | 1.00 | LMNA (0.52) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL27619877 | 0.88 | RECQL (0.52) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL11110675 | 0.87 | LMNA (0.51) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL8558118 | 0.86 | DHODH (0.51) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL6148121 | 0.84 | MEN1 (0.58) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL8499352 | 0.83 | DHODH (0.59) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL3841651 | 0.83 | LMNA (0.55) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL6934698 | 0.81 | LMNA (0.53) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL3142288 | 0.81 | LMNA (0.52) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL6846510 | 0.80 | LMNA (0.49) | LMNAMAPK1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465855-A | ANTIREUMATIC & ANTIINFLAMMATORIES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1984-08-14 | — | — | US | disclosed |
| US-4385004-A | Esters of ortho-allylphenol useful for the preparation of arylacetic acid derivatives | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-05-24 | — | — | US | disclosed |
| US-4317920-A | ANTIRHEUMATIC AGENTS, ANTIINFLAMMATORY AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-03-02 | — | — | US | disclosed |