Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934698 | 0.84 | LMNA (0.53) | LMNAMAPK1MEN1KMT2AESR1 | |
| SCHEMBL3841651 | 0.83 | LMNA (0.55) | LMNAMAPK1MEN1KMT2AESR1 | |
| SCHEMBL8499352 | 0.83 | DHODH (0.59) | LMNAMAPK1MEN1KMT2AESR1 | |
| SCHEMBL6845461 | 0.82 | LMNA (0.46) | LMNAMAPK1MEN1KMT2AESR1 | |
| SCHEMBL28027226 | 0.82 | CYP3A4 (0.50) | LMNAMAPK1MEN1KMT2AESR1 | |
| SCHEMBL10180459 | 0.82 | LMNA (0.48) | LMNAMAPK1MEN1KMT2AESR1 | |
| SCHEMBL3142288 | 0.81 | LMNA (0.52) | LMNAMAPK1MEN1KMT2AESR1 | |
| SCHEMBL15936332 | 0.81 | ENPP1 (0.55) | LMNAALDH1A1CNR2 | |
| SCHEMBL6148121 | 0.81 | MEN1 (0.58) | LMNAMAPK1MEN1KMT2AESR1 | |
| SCHEMBL11110671 | 0.80 | LMNA (0.52) | LMNAMAPK1MEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481967-A1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | Sumitomo Chemical Company, Limited (JP) | 2004-12-01 | — | — | EP | disclosed |