Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109415 | 0.89 | NR3C1 (0.54) | NR3C1PGRL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL11107380 | 0.78 | NR3C1 (0.48) | NR3C1KDM4EHSD17B10HTR2ACYP2D6 | |
| SCHEMBL11107772 | 0.77 | NR3C1 (0.48) | NR3C1PGRKDM4EHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL11113390 | 0.77 | NR3C1 (0.47) | NR3C1PGRKDM4EHSD17B10HTR2A | |
| SCHEMBL11112142 | 0.74 | NR3C1 (0.42) | NR3C1PGRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL11105960 | 0.74 | NR3C1 (0.39) | NR3C1L3MBTL1KDM4EHSD17B10HTR2A | |
| SCHEMBL11103784 | 0.74 | HPGD (0.61) | NR3C1KDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL11109246 | 0.73 | CES2 (0.44) | NR3C1PGRL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL11107791 | 0.73 | NR3C1 (0.44) | NR3C1PGRKDM4EHSD17B10HPGD | |
| SCHEMBL11111130 | 0.72 | KDM4E (0.49) | NR3C1PGRL3MBTL1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |