Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | PNMT | P11086 | 4/20 | 0.43 |
| ▸ | AHR | P35869 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337925 | 0.93 | ALOX15 (0.67) | ALOX15HSD17B10PNMTAHRCMA1 | |
| SCHEMBL7341760 | 0.88 | ALOX15 (0.63) | ALOX15HSD17B10PNMTAHRCMA1 | |
| SCHEMBL7858934 | 0.88 | ALOX15 (0.63) | ALOX15HSD17B10PNMTAHRCMA1 | |
| SCHEMBL2087881 | 0.81 | ALOX15 (1.00) | ALOX15HSD17B10PNMTAHRGAA | |
| SCHEMBL31546300 | 0.81 | ALOX15 (1.00) | ALOX15HSD17B10PNMTAHRGAA | |
| SCHEMBL7866841 | 0.79 | ALOX15 (0.67) | ALOX15HSD17B10AHRGAANPSR1 | |
| SCHEMBL894019 | 0.79 | ALOX15 (0.67) | ALOX15HSD17B10PNMTAHRCMA1 | |
| SCHEMBL6905658 | 0.79 | HTR2A (0.45) | PNMTAHRCMA1CA1CA2 | |
| SCHEMBL31196699 | 0.79 | HTR2A (0.45) | PNMTAHRCMA1CA1CA2 | |
| SCHEMBL31196698 | 0.79 | HTR2A (0.45) | PNMTAHRCMA1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434171-A | NEUROLEPTIC, ANTIDEPRESSANT | SANDOZ LTD. (CH) | 1984-02-28 | — | — | US | disclosed |