SCHEMBL11111069

SCHEMBL11111069

CCCCCCCN1C(=O)C(c2ccccc2)NC1=S

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
FAAH O00519 1/20 0.51
CNR2 P34972 3/20 0.48
CNR1 P21554 1/20 0.48
CDC25A P30304 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 1/20 0.43
ALOX12 P18054 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP19A1 P11511 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22265963 0.87 LMNA (0.68) LMNAADORA3FAAHCNR2CNR1
SCHEMBL11017764 0.83 LMNA (0.73) LMNAADORA3CA1CA2ALDH1A1
SCHEMBL11459127 0.81 LMNA (0.71) LMNAADORA3CNR2CNR1CDC25A
SCHEMBL14560424 0.75 CNR2 (0.65) FAAHCNR2CNR1CDC25AALDH1A1
SCHEMBL7606899 0.72 FAAH (0.41) LMNAADORA3FAAHCNR2CNR1
SCHEMBL8364956 0.72 CYP19A1 (0.76) CNR2CNR1CDC25AALDH1A1KMT2A
Ethotoin SCHEMBL34301 0.71 LMNA (1.00) LMNAADORA3SMN1; SMN2ALDH1A1KMT2A
Ethotoin SCHEMBL34302 0.71 LMNA (1.00) LMNAADORA3SMN1; SMN2ALDH1A1KMT2A
SCHEMBL14560486 0.70 CYP19A1 (0.57) FAAHCNR2CNR1CDC25AALDH1A1
SCHEMBL11460061 0.70 CA1 (0.42) LMNACA1CA2CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0111919-A2 Multicolor photographic elements containing silver iodide grains EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-06-27 EP disclosed