Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | CDC25A | P30304 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560417 | 0.93 | CNR2 (0.55) | CNR2CNR1CDC25AALDH1A1CYP19A1 | |
| SCHEMBL22265963 | 0.78 | LMNA (0.68) | CNR2CNR1CDC25ACES1PTGS1 | |
| SCHEMBL8364956 | 0.77 | CYP19A1 (0.76) | CNR2CNR1CDC25ACES1ALDH1A1 | |
| SCHEMBL14560605 | 0.77 | CNR2 (0.97) | CNR2CNR1CDC25AALDH1A1ALDH2 | |
| SCHEMBL14560421 | 0.75 | MAPT (0.48) | CNR2CNR1ALDH1A1 | |
| SCHEMBL14560505 | 0.75 | CNR2 (0.48) | CNR2CNR1CDC25AALDH1A1CYP19A1 | |
| SCHEMBL11111069 | 0.75 | LMNA (0.55) | CNR2CNR1CDC25AFAAHALDH1A1 | |
| SCHEMBL14560486 | 0.75 | CYP19A1 (0.57) | CNR2CNR1CDC25ACES1MGLL | |
| SCHEMBL428093 | 0.73 | GBA1 (0.50) | CNR2CNR1CDC25ACES1PTGS1 | |
| SCHEMBL23731163 | 0.72 | CES1 (0.68) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |