Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | FAP | Q12884 | 4/20 | 0.39 |
| ▸ | PREP | P48147 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 10/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11113477 | 0.86 | DPP4 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1046072 | 0.83 | DPP4 (0.46) | DPP4FAPPREPF2PRSS1 | |
| SCHEMBL1046070 | 0.83 | DPP4 (0.46) | DPP4FAPPREPF2PRSS1 | |
| SCHEMBL4330609 | 0.81 | FAP (0.41) | DPP4FAPPREPF2PRSS1 | |
| SCHEMBL4327210 | 0.81 | FAP (0.41) | DPP4FAPPREPF2PRSS1 | |
| SCHEMBL11112657 | 0.80 | DPP4 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11515849 | 0.80 | F2 (0.40) | DPP4FAPPREPF2NPSR1 | |
| SCHEMBL11515844 | 0.80 | F2 (0.40) | DPP4FAPPREPF2NPSR1 | |
| SCHEMBL464681 | 0.80 | PREP (0.55) | DPP4FAPPREPF2PRSS1 | |
| SCHEMBL11111706 | 0.79 | SMN1; SMN2 (0.57) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115473-A2 | Substituted pyrrolidinone derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1984-08-08 | — | — | EP | disclosed |