Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515849 | 1.00 | F2 (0.40) | F2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL29240007 | 0.87 | ALDH1A1 (0.42) | CYP3A4CYP2C9PKMCYP2C19ALDH1A1 | |
| SCHEMBL20908682 | 0.86 | F2 (0.48) | F2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL1046070 | 0.84 | DPP4 (0.46) | F2NPSR1DPP4PREPFAP | |
| SCHEMBL1046072 | 0.84 | DPP4 (0.46) | F2NPSR1DPP4PREPFAP | |
| Hydrochloric Acid SCHEMBL5315838 | 0.82 | ALDH1A1 (0.41) | F2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL4330609 | 0.82 | FAP (0.41) | F2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL4327210 | 0.82 | FAP (0.41) | F2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL5178008 | 0.81 | DPP4 (0.48) | F2FKBP1AKDM4EDPP4PREP | |
| SCHEMBL464681 | 0.81 | PREP (0.55) | F2NPSR1DPP4PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159980-A | Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-3947569-A | Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |