Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 7/20 | 0.55 |
| ▸ | FAP | Q12884 | 6/20 | 0.55 |
| ▸ | DPP4 | P27487 | 5/20 | 0.55 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439280 | 0.87 | PREP (0.56) | PREPFAPDPP4F2NPSR1 | |
| SCHEMBL4327210 | 0.87 | FAP (0.41) | PREPFAPDPP4F2NPSR1 | |
| SCHEMBL4330609 | 0.87 | FAP (0.41) | PREPFAPDPP4F2NPSR1 | |
| SCHEMBL20908682 | 0.85 | F2 (0.48) | PREPFAPDPP4F2NPSR1 | |
| SCHEMBL30493625 | 0.85 | DPP4 (0.60) | PREPFAPDPP4 | |
| SCHEMBL1046072 | 0.84 | DPP4 (0.46) | PREPFAPDPP4F2NPSR1 | |
| SCHEMBL1046070 | 0.84 | DPP4 (0.46) | PREPFAPDPP4F2NPSR1 | |
| SCHEMBL13012657 | 0.82 | FAP (0.56) | PREPFAPDPP4F2P2RX7 | |
| SCHEMBL28913603 | 0.81 | FAP (0.61) | PREPFAPDPP4F2 | |
| SCHEMBL11515849 | 0.81 | F2 (0.40) | PREPFAPDPP4F2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065366-A1 | CYCLIC AMINO ACID MOLECULES AND METHODS OF PREPARING THE SAME | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065366-A1 | CYCLIC AMINO ACID MOLECULES AND METHODS OF PREPARING THE SAME | DNPEP, ANPEP, BCAT1 | PREP 35/4885FAP 148/4885DPP4 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.