Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MMP8 | P22894 | 3/20 | 0.56 |
| ▸ | MMP12 | P39900 | 3/20 | 0.56 |
| ▸ | MMP13 | P45452 | 3/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15754219 | 0.87 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9AMMP8MMP12 | |
| SCHEMBL11108606 | 0.85 | L3MBTL1 (0.59) | L3MBTL1NPC1RAB9AMMP8MMP12 | |
| SCHEMBL27728327 | 0.84 | L3MBTL1 (0.58) | L3MBTL1NPC1RAB9AMMP8MMP12 | |
| SCHEMBL11113183 | 0.83 | SMN1; SMN2 (0.58) | L3MBTL1NPC1RAB9AMMP8MMP12 | |
| SCHEMBL11105772 | 0.80 | RARB (0.57) | L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL894337 | 0.80 | HPGD (0.56) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL11108949 | 0.80 | AKR1C3 (0.72) | AKR1C3TAAR1ALDH1A1MAPTKMT2A | |
| SCHEMBL3207695 | 0.80 | MMP8 (0.60) | L3MBTL1NPC1RAB9AMMP8MMP12 | |
| SCHEMBL11105745 | 0.79 | MMP1 (0.53) | L3MBTL1NPC1RAB9AMMP8MMP12 | |
| SCHEMBL11105080 | 0.79 | L3MBTL1 (0.53) | L3MBTL1NPC1RAB9AMMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443477-A | ANTICOAGULANTS, ANTILIPEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-17 | — | — | US | disclosed |
| EP-0031954-B1 | SULPHONAMIDES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1984-03-14 | — | — | EP | disclosed |
| EP-0031954-A2 | Sulphonamides, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-07-15 | — | — | EP | disclosed |